Claude, Duke of Guise

Claude of Lorraine, Duke of Guise (20 October 1496 – 12 April 1550) was a French aristocrat and general. He became the first Duke of Guise in 1528 and gounded the House of Guise itself a cadet branch of the House of Lorraine.

Marriage
9 June 1513, he married Antoinette de Bourbon, daughter of François, Count of Vendôme.

Issue

 * 1) Marie of Lorraine (Mary of Guise) (1515–1560) married firstly Louis II d'Orléans, Duke of Longueville and secondly king James V of Scotland and had issue, including Mary, Queen of Scots and had issue.
 * 2) Francis, Duke of Guise (1519–1563)
 * 3) Louise of Lorraine (10 January 1520, – 18 October 1542); married Charles I, Duke of Arschot.
 * 4) Renée of Lorraine (2 September 1522 – 3 April 1602), Abbess of Saint Pierre, Reims.
 * 5) Charles of Lorraine (1524–1574)  Duke of Chevreuse, Archbishop of Reims, and Cardinal of Lorraine.
 * 6) Claude, Duke of Aumale (1526–1573)
 * 7) Louis I, Cardinal of Guise (1527–1578)
 * 8) Philippe of Lorraine (3 September 1529 – 24 September 1529)
 * 9) Peter of Lorraine (born 3 April 1530) died young.
 * 10) Antoinette of Lorraine (31 August 1531 – 6 March 1561) Abbess of Faremoutiers
 * 11) François of Lorraine, Grand Prior (18 April 1534, – 6 March 1563)
 * 12) René of Lorraine, Marquis of Elbeuf (1536–1566) married Louise de Rieux and had isue.